Aprotinin is a serine protease inhibitor used medically to reduce the systemic inflammatory response associated with cardiopulmonary bypass surgery, and also as a generalized protease inhibitor in R&D, cell culture and manufacturing applications. New medical indications and greater use in industrial applications are expected to increase demand for reliable sources of aprotinin.

The various aprotinin-containing products on the market today are produced from raw material obtained by extraction of bovine lungs, creating concerns over consistent availability and product safety.

KBP has successfully produced bovine-identical recombinant aprotinin using the proprietary GENEWARE® plant-virus-based biomanufacturing system — a eukaryotic transient-expression technology that has produced a wide array of proteins in non¬food/feed, non-transgenic plants. Recombinant aprotinin produced by this method has the same biological activity as its animal-extracted counterpart, is considerably purer than the approved pharmaceutical product reference standard, and can be obtained reliably in sufficient quantities to meet worldwide demand without the safety and supply concerns associated with animal- and especially bovine-derived products.

KBP has extensive biomanufacturing experience with products produced through the Company’s proprietary technology. Aprotinin is one of the newest products offered by KBP for non-clinical applications. KBP’s Aprotinin is currently available in a saline solution at >5.7 TIU/mg of protein. If you would like more information or to place order please call 270-689-2570 or email info@kbpllc.com.

 

 

KBP will provide bulk pricing for orders over 100mg.  Lyophilized material is available upon request.   

 

Size	Price
1 mg	$45.90
5 mg	$63.75
10 mg	$89.75
25 mg	$127.50
100 mg	$402.85